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PCO Management

Pro‐Sexual Nutrient for Male‐Sexual‐Dysfunction [FSSAI Category] Deranged libido, erection and orgasm are only a part of the male sexual dysfunction. However, many individuals in the present day scenario are unsuspecting victims of a disorder which destroys the life of males who are afflicted by this disorder. Premature ejaculation occurs when a man ejaculates sooner during sexual intercourse than he or his partner would like. Premature ejaculation is a common sexual complaint

Simplified diagnostic criteria for premature ejaculation

i. Ejaculation that always or nearly always occurs prior to or within about 1 min of vaginal penetration
ii. Inability to delay ejaculation on all, or nearly all, vaginal penetrations and
iii. Negative personal consequences, such as distress, bother, frustration and/or the avoidance of sexual intimacy

Symptoms of Premature Ejaculation [PE]

The primary symptom of premature ejaculation is the inability to delay ejaculation for more than one minute after penetration. Premature ejaculation can be classified as lifelong (primary) or acquired (secondary). Lifelong premature ejaculation occurs all or nearly all of the time beginning with the first sexual encounter. Acquired premature ejaculation has the same symptoms but develops after having previous sexual experiences without ejaculatory problems.

Possible Causes

The exact cause of premature ejaculation isn't known. While it was once thought to be only psychological, doctors now know premature ejaculation is more complicated and involves a complex interaction of psychological and biological factors.

Psychological Causes

Some doctors believe that early sexual experiences may establish a pattern that can be difficult to change later in life, Such as:
i. Situations in which the individual hurries to reach climax in order to avoid being discovered
ii. Guilty feelings that increase the individuals tendency to rush through sexual encounters

Other factors that can play a role in causing premature ejaculation include:
Erectile Dysfunction
Anxiety
Relationship Problems

Biological Causes

A number of biological factors may contribute to premature ejaculation, including:
i. Abnormal hormone levels
ii. Abnormal levels of chemicals called neurotransmitters in the human brain
iii. Abnormal reflex activity of the ejaculatory system
iv. Certain thyroid problems
v. Inflammation and infection of the prostate or urethra
vi. Inherited traits

Risk Factors

1. Erectile Dysfunction ‐ At increased risk of premature ejaculation if you occasionally or consistently have trouble getting or maintaining an erection. Fear of losing your erection may cause you to consciously or unconsciously hurry through sexual encounters.
2. Health Problems ‐ If you have a serious or chronic medical condition, such as heart disease, you may feel anxious during sex and may unknowingly rush to ejaculate.
3. Stress ‐ Emotional or mental strain in any area of your life can play a role in premature ejaculation, often limiting your ability to relax and focus during sexual encounters.

Premature Ejaculation Treatment

A range of drugs are currently used by clinicians for the management of PE including antidepressants, local anesthetic agents and phosphodiesterase type 5 inhibitors. Whether the medication is used regularly or on demand is an important consideration for patients when choosing the most appropriate drug for the treatment of their PE. An on‐demand drug offers the flexibility of using the medication just prior to sexual intercourse, thereby reducing the risks of side effects associated with the drug for the rest of the time. A recent introduction into the Indian market is a short acting on‐demand SSRI Dapoxetine. The major problem with this medication is that it has to be taken at least 1‐2 hours prior to the sexual act. In a country like India, planned sex is virtually impossible, as the culture and custom are different unlike the western world. Although many Physicians consider this drug relatively safe and with few side effects, the major side effects that have been observed are nausea, diarrhea, headache, dizziness, decreased libido, erectile dysfunction [ED] and severe delays in ejaculation on long term use. The successful use of a nutraceutical, Hypericum containing Hypericin and Hyperforin [St. John's Wort] in Psychiatry paved way for the use of this active ingredient in a recipe along with other ingredients such as Butea superba, Piper longum, Turnera diffusa and Crocus sativus for treating premature ejaculation. The safety profile of these ingredients has been documented and has produced good clinical results in individuals with PE. This combination of nutraceutical ingredients has been aptly titled Lvate. The combination, of these ingredients has improved patient compliance and also the need for multiple drug therapy, thereby eliminating the unwanted, adverse drug reactions.

Absorption

Despite the mechanism of action being elucidated for all the active ingredients, the absorption patterns of the Individual and the ingredients combined in Lvate have not been studied and documented.

Metabolism

The metabolism and metabolite excretion patterns of the individual and combined ingredients of Lvate have not been studied.

Carcinogenesis, Mutagenesis

The nutraceutical supplement Lvate has not been administered to pregnant or lactating women as the supplement is currently recommended only for males.

Warnings & Precautions

The ingredients of Lvate have been used for centuries, and their active principles for over 2‐3 decades. It is advisable to inquire with the patients if they have taken similar nutraceutical preparations or one or more ingredients of the preparation, to prevent any adverse events. Concurrent administration of synthetic drugs has resulted in drug interactions with no fatalities. The physician needs to be updated on the drug interactions mentioned in drug interactions. Although one or more of the individual ingredients contained in Lvate is being used in female sexual dysfunction, the drug should not be administered to pregnant or lactating mothers, as the effects of the nutraceutical supplement have not been studied in this population.

Adverse Drug Reactions

No serious adverse drug reactions have been reported with use of Lvate; however, in susceptible individuals, mild to moderate GI upset has been noted that usually resolves during the course of the treatment. Headache and anorgasmia have been reported in very high doses of 900 – 1500 mg of Hypericum per day.

Drug Interactions

Drug interactions of mild to moderate severity have been noted with Carbamazepine, Cyclosporine, Nifedepine, Theophylline, Midazolam, SSRIs, and consumption of alcohol.

Usage in Special Population

1. Pregnancy & Lactation – The use and effects of Lvate have not been studied in pregnancy and lactating mothers. 2. Pediatric Use – The use/ safety of Lvate has not been studied in pediatric population 3. Renal and Hepatic Insufficiency – During animal and human clinical studies, no changes were observed in either renal or hepatic parameters. However, it is advisable to avoid the use of Lvate in cases of hepatic or renal failure, as the absorption, metabolism, distribution and excretion patterns of the active ingredients have not been studied in these classes of patients.

Dosage and Administration

The recommended dosage of Lvate is 1‐2 Capsules at bedtime with warm milk for a minimum duration of 90 days and thereafter can be extended at the discretion of the treating physician. The vegetable capsule of Lvate should be swallowed whole and should not be opened or chewed as the active ingredients are in a pellet form in the capsule. A gap of 2‐3 hours must be maintained between the consumption of other medications and Lvate capsules to avoid drug interactions.

How Supplied

Each strip contains 10 Vegetable Capsules and each box contains 10 Strips of 10 Vegetable Capsules.

Storage

The carton must be stored at the ambient temperature mentioned on the carton, preferably at temperatures below 25⁰C, away from direct sunlight. Do not use the drug if the capsules are leaking or damaged.

Unyte

Unite for paternity

You might remember my post where I whined about my husband failing to perform? He wouldn’t get started at all, even with a blow job or a hand job, or he would come in just 1—3 minutes. At first I was like: OK, where do all those adult film dudes get their stamina — we tried everything you can think of, from Viagra and other boner pills to yoga or that tantric thing. Bullshit — his dick remained limp, sex didn’t last more than a couple of minutes. In about 6 months I gave up. I decided that’s his genes and his physical condition, and there’s nothing to do about it. After all, I can’t say I wanted him as before, knowing all will end up in nothing, I won’t be satisfied, he’ll be upset. I felt my husband was totally losing confidence. Help came when I expected it no more... I came across an interview with a prominent ED (erectile dysfunction) researcher, where she said any man can perform for up to 2 hours. That’s something I’m interested in, I thought. According to her, she’s using special natural extractions — horny goat, wild yam, Corean ginseng, lycorice root, potency wood, oyster shell extracts — all in a harmless herbal pill which you can buy without prescription. This complex herbal medicine boosts sex hormone production and gives her male counterparts the stiffie of an 18 year old and the endurance of a porn star. Based on the ingredients she listed, I searched for the perfect product that would "fix" hubbies ED. Original TestoUltra pills with TRTT technology have the correct ingredients, so I found their website on the net and decided to make an order. I was really surprised that they had a special promo offer, so I got one without hesitating. What is the result? The pills arrived soon, and I couldn’t wait for us to go to bed — before he fell asleep, I gave him a pill saying that it is just a vitamin. I’m uncomfortable telling you the amazing experience but… since we’ll never meet offline I will tell you the details: In less than an hour my husband woke up with a rock hard super stiff erection, and will you believe me when I say we banged for 1 hour and 47 minutes! Cosmic pleasure, lots of sweat and screaming — a perfect ride, the best I’ve ever had. I did expect some improvement, but this was a man I never knew before. The website says these pills should also boost my better half’s libido size, and that’s what we’re going to check in a couple of weeks. Well, I still find it hard to believe that this stuff turned him into a wild animal in bed — and all for a price of one movie ticket and without any stupid prescription. I find the effect worth every penny (I already ordered three more packs) — life is short, and I’m not the kind of girl that scrimps on pleasures. So I can definitely recommend these amazing TestoUltra pills for anyone who wants to improve their sexual experience. Don’t hesitate to use that special offer for TestoUltra. On top of my Hubby’s erections coming back, now he also lasts longer than ever before!

markeit

Guaifenesin 200mg Tablets USP

Markeit Tablet Markeit Tablet is an expectorant that is used in the treatment of a cough. This medicine should be used with extreme caution in patients less than 2 years of age and only under the supervision of your doctor. What is it prescribed for? Cough

Side effects

Major & minor side effects for Markeit Tablet Diarrhea Dizziness Headache Hives Nausea or Vomiting Skin Rash Stomach pain Commonly asked questions for Markeit Tablet Onset of action The effect of this medicine can be observed within 30 minutes of administration of the dose. Duration of effect The effect of this medicine lasts for an average duration of 4 to 12 hours. Safe with alcohol? Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption. Is it habit forming? No habit-forming tendencies were reported. Usage in pregnancy? This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Usage while breast-feeding? This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects

Fertilate

Fertility Incysted

Herbal cures for uterine fibroids

It has become so common. Many young women are now complaining of uterine fibroids. Alternative names are uterine leiomyoma, fibromyoma, myoma, or fibroids. Recent studies have shown that uterine fibroids are the most common non-malignant Growths in women of child bearing age. Common symptoms may include heavy or painful periods; prolonged menstrual periods; bleeding between periods; pelvic pain or Low back pain; ‘fullness’in the lower abdomen, with or without urinary or rectal Symptoms due to compression; and reproductive problems, such as infertility, multiple miscarriages, or early onset of labour during pregnancy. The significant symptoms and progressive nature of the disease frequently require Hysterectomy (removal of the womb), which is associated with surgical morbidity and Precludes the opportunity for future childbirth. It has also been reported that the fibroids Grew back after surgical evacuation. But recent studies have validated more herbal remedies to provide permanent solution To the menace without adverse side effects.

Turmeric

Turmeric is a spice that comes from the root of Curcuma longa, a member of the ginger family, Zingaberaceae. It contains the active ingredient curcumin. Curcumin is a bright yellow chemical produced by some plants. It is the principal curcuminoid of turmeric. (It is sold as an herbal supplement, cosmetics ingredient, food flavouring, and food colouring. Thai researchers have successfully decreased the size of uterine fibroids after six Months of daily oral administration of turmeric. The study titled Curcuminin Reduction Size of Myoma Uteri was published in Thai Journal of Obstetrics and Gynecology. Ultra sound measurement of size of leiomyoma was done before treatment with curcumin was started. Main out comes measure was size of leiomyoma. Size of leiomyoma was compared between before and after taking curcumin for six months. The results showed the mean diameter of leiomyoma were statistically different at Before and after three and six month’s curcumin intake. And both mean volume of Leiomyoma was statistically different at before and after three and six month’s curcumin intake. Adverse effect of curcumin was not found. The researchers from Heliopolis Research Center,Cairo and Department of obstetrics And Gynaecology, Faculty of Medicine, Ain Shams University Cairo Egypt noted: “Curcumin,the active ingredient in turmeric,is known for its antitumor,anticancer, Strong anti-inflammatory,antioxidative,antiangiogenic,proapoptotic,antiamyloid, antiarthritic,potent inhibitors of cytochrome p450,reduced cholesterol level. Uterine fibroid are the most common pelvic tumours and occur in 20 to 25 percent of premenopausal women.

Fighting-Fibroid

Estimates show that 20-25 percent of women are at risk of experiencing these slow-developing growths by the age of 40-and more than half of women are likely to have them by the time they Reach menopause. Many women are told that surgery is the only cure for fibroids. But that's not always the case. There are several effective natural therapies-including specific foods, herbs, and supplements-that can help you avoid an invasive procedure such as uterine fibroid surgery. These natural, hormone-balancing treatments worked for Jennifer-she didn't need a hysterectomy to find relief from fibroids.

Signs & Symptoms

Uterine fibroids are composed of connective tissue and muscle that develop on the inside or outside walls of the uterus. Often found in groups, fibroids can be round and firm, soft, and/or rock hard. And they vary in size from microscopic to quite large. It is common for a woman to have fibroids that are symptom-free. In fact, as many as75 percent of women are unaware that they have fibroids. For those who experience symptoms , the most common include • Increased menstrual symptoms-pain, heavy bleeding, irregular periods, mid-cycle bleeding • Iron deficiency due to increased blood loss • Bloating, pressure, heaviness, or enlarged abdomen • Back pain • Excessive vaginal discharge • Frequent urination or bladder irritation • Pain or bleeding with intercourse • Constipation • Infertility

How Estrogen Dominance Promotes Fibroid Growth

Fibroid growth is stimulated by estrogen. Research has shown that fibroids have a significantly higher concentration of estrogen receptors than normal uterine muscle. Therefore, it's not surprising that fibroids typically develop in a woman's reproductive years and Lessen considerably (or disappear completely) after menopause. Many women with fibroids suffer from estrogen" dominance"-having higher levels of estrogen relative to progesterone. Certain medications, including birth control pills ,fertility drugs, and hormone replacement therapy, can actually create a state of estrogen" dominance" in the body. Other factors that promote excess estrogen include liver congestion , bowel toxicity, inflammation, stress, hypothyroidism, low progesterone, and exposure to environmental estrogens(e.g.,pesticides, BPA, and/or phthalates).

Pantozone

Pantoprazole 40mg Tablets

Pantozone-D

Pantoprazole 40mg+ Domperidone 30mg Capsules.

Pantozone-Inj

Pantoprazole 40mg injection

Highlights for pantozone

Pantoprazole oral tablet is available as both a generic and a brand-name drug. Brand-name: Protonix. Pantoprazole comes in three forms: an oral tablet, an oral liquida suspension, and an intravenous (IV) form that’s injected into your vein by a healthcare provider. Pantoprazole oral tablet is used to reduce the amount of stomach acid your body makes. It helps treat painful symptoms caused by conditions such as gastroesophageal reflux disease (GERD).

What is pantoprazole?

Pantoprazole oral tablet is a prescription drug that’s available as the brand-name drug Protonix. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Pantoprazole comes in three forms: an oral tablet, an oral liquid suspension, and an intravenous (IV) form that’s injected into your vein by a healthcare provider.

Furantoin

Nitrofurantoin 100mg Tablets

Highlights for nitrofurantoin

Nitrofurantoin oral capsule is available as both generic and brand-name drugs. Brand-names: Macrobid and Macrodantin. Nitrofurantoin is also available in an oral suspension. Nitrofurantoin oral capsule is used to prevent and treat urinary tract infections that are caused by certain bacteria.

What is nitrofurantoin?

Nitrofurantoin is a prescription drug that comes as an oral capsule and an oral suspension. Nitrofurantoin oral capsule is available as the brand-name drugs Macrobid and Macrodantin. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.

Folimar

Folic Acid 5mg Tablets

Folic Acid: Everything You Need to Know

Folic acid is the synthetic form of folate, a water-soluble vitamin also known as vitamin B9. It does not occur naturally in food but is frequently added to supplements and refined grain products, such as bread and cereals. Since folic acid is different from natural folate, it must be converted into an active form before your body can use it. Your genetics affect how quickly this conversion takes place, so folic acid is a hot topic in current nutrition research. This article discusses folic acid, its benefits, sources, your risk of deficiency and more.

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